Disentangling
Home
About this project
Disentangling penicillin resistance and compensatory adaption in pneumococci
by combining genomics and molecular microbiology
Inheritance patterns of the unitigs
This analysis investigates the hits from the GWAS analysis:
Apr 26, 2023
Sequences of interest
In this analysis, we investigate specific genes of interest that are potentially involved in penicillin resistance. One…
Jan 11, 2023
Conditional GWAS
Here we present the results of a genome-wide association study (GWAS) conducted using pyseer
(John A. Lees et al. 2018)
, a tool for identifying genetic associations with complex traits. The GWAS using the linear mixed effects model such that the minimum inhibitory…
Jan 3, 2023
Penicillin binding proteins
PBPs are proteins that can attach to
\(\beta\)
-lactam antibiotics like penicillin. These proteins are essential for making the bacterial cell wall, and when they are bound by penicillin, the…
Dec 14, 2022
Serotypes, GPSC-clusters, and MLST types
The following plots presents an…
Nov 23, 2022
An overview of the data
The goal of this project is to determine mutations and factors that are involved in penicillin resistance. We have collected a data set with…
Nov 4, 2022
No matching items